SOUTH SAN FRANCISCO, CA--(Marketwire - June 03, 2008) - Cytokinetics, Incorporated (NASDAQ: CYTK) announced today that three abstracts summarizing data from clinical trials relating to its oncology programs were presented at the 2008 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, IL. Two of these abstracts related to clinical trials evaluating ispinesib, one trial sponsored by Cytokinetics and the other by the National Cancer Institute (NCI). The third abstract related to a clinical trial sponsored by Cytokinetics evaluating SB-743921. Ispinesib and SB-743921 are novel, chemically distinct, small molecule inhibitors of kinesin spindle protein (KSP), a mitotic kinesin essential for proper cell division. Both drug candidates have arisen from a broad strategic collaboration between Cytokinetics and GlaxoSmithKline (GSK) to discover, develop and commercialize novel small molecule therapeutics targeting human mitotic kinesins for applications in the treatment of cancer and other diseases.
