Mela Sciences to Present at Upcoming Investor Conferences

IRVINGTON, NY--(Marketwire - May 27, 2010) - MELA Sciences, Inc. (NASDAQ: MELA) announced today that Joseph V. Gulfo, MD, President and CEO will present at upcoming investor conferences in New York City.

-- The 9th Annual Needham Healthcare Conference taking place June 9-10, 2010 at The New York Palace hotel. Dr. Gulfo is scheduled to present on Wednesday, June 9, 2010 at 2:00 pm ET.

-- The Jefferies Global Life Sciences Conference taking place June 8-11, 2010 at the Grand Hyatt hotel. Dr. Gulfo is scheduled to present on Thursday, June 10, 2010 at 8:00 am ET.

To access live webcasts of these presentations, visit www.melasciences.com. A replay of this presentation will be available on the company’s website for thirty days following the presentation.

About MELA Sciences, Inc.

MELA Sciences, Inc. is a medical technology company focused on developing MelaFind®, a non-invasive and objective computer vision system intended to aid in the early detection of melanoma. MELA Sciences designed MelaFind to assist in the evaluation of pigmented skin lesions, including atypical moles, which have one or more clinical or historical characteristics of melanoma, before a final decision to biopsy has been rendered. MelaFind acquires and displays multi-spectral (from blue to near infrared) digital images of pigmented skin lesions and uses automatic image analysis and statistical pattern recognition to help identify lesions to be considered for biopsy to rule out melanoma.

The MelaFind Pre-Market Approval (PMA) application was filed with the U.S. Food and Drug Administration (FDA) in June 2009 and is currently under review at the FDA. MELA Sciences cannot predict either the timing of the FDA’s decision on the PMA application or the outcome. FDA approval is required prior to marketing MelaFind in the United States.

For more information on MELA Sciences, visit www.melasciences.com.

Safe Harbor

This press release includes “forward-looking statements” within the meaning of the Securities Litigation Reform Act of 1995. These statements include but are not limited to our plans, objectives, expectations and intentions and other statements that contain words such as “expects,” “contemplates,” “anticipates,” “plans,” “intends,” “believes” and variations of such words or similar expressions that predict or indicate future events or trends, or that do not relate to historical matters. These statements are based on our current beliefs or expectations and are inherently subject to significant uncertainties and changes in circumstances, many of which are beyond our control. There can be no assurance that our beliefs or expectations will be achieved. Actual results may differ materially from our beliefs or expectations due to economic, business, competitive, market and regulatory factors.