Ambrosia Bio today announced that Ambrosia Bio will leverage Ginkgo Enzyme Services, including its proprietary chassis organisms, to develop an expression strain for the scalable production of the Ambrosia Bio proprietary enzymes used for the conversion of feedstock into allulose.
Ambrosia aims to make the production of allulose, a next-generation sugar replacement, more scalable and affordable JERUSALEM and BOSTON, June 29, 2023 /PRNewswire/ -- Ambrosia Bio, an Israeli foodtech company developing novel bioprocesses for the global sugar replacement industry, and Ginkgo Bioworks (NYSE: DNA), which is building the leading platform for cell programming and biosecurity, today announced that Ambrosia Bio will leverage Ginkgo Enzyme Services, including its proprietary chassis organisms, to develop an expression strain for the scalable production of the Ambrosia Bio proprietary enzymes used for the conversion of feedstock into allulose. Allulose is an FDA-approved rare sugar that is found in figs, raisins, wheat, maple syrup, and molasses but occurs naturally only in small amounts. Unlike other currently available sweeteners, allulose has a low caloric value – typically under 10% compared to equivalent amounts of sucrose – giving it the ability to minimally impact blood glucose and insulin levels while maintaining sugar’s sensory and culinary properties. Mass production of allulose requires enzymatic conversion of common carbohydrates, but many of the natural enzymes available on the market today lack stability and effectiveness. Over the past three years of stealth mode development, Ambrosia Bio has successfully developed a unique bioprocess using proprietary enzymes alongside a complementary production process to affordably and scalably convert lower-margin feedstocks (e.g., sugar and starch) into rare sugars and specialized ingredients such as allulose. Ambrosia Bio’s proprietary approach has remarkable process stability and fidelity across long periods of time and temperature fluctuations, proving highly effective relative to current benchmarks. Ultimately, Ambrosia Bio, whose product is being evaluated in applications and formulations by customers that include one of the largest international food and beverage producers as well as a global sugar manufacturer, aims to replace the costly and cumbersome allulose production processes currently used by ingredient manufacturers worldwide, helping to democratize the global use of allulose. To further optimize its process, Ambrosia Bio will leverage Ginkgo Enzyme Services, an end-to-end service powered by ultra-high throughput screening and machine learning-guided protein design, to aid its goal of producing an optimized version of its proprietary enzyme in a productive expression strain. In particular, Ambrosia Bio seeks to benefit from access to Ginkgo’s extensive strain engineering Codebase, as well as Ginkgo’s Foundry capabilities in enzyme expression and analytical chemistry, to develop a more scalable and affordable commercial allulose solution. “Ginkgo has established itself as a global leader in the synthetic biology ecosystem and precision fermentation space,” said Ziv Zwighaft, Founder and CEO at Ambrosia Bio. “With end-to-end capabilities, Ginkgo is a one-stop shop that can enable Ambrosia Bio to expand global allulose availability. We aim to provide affordable options for key sugar production players, as well as leading global brands in the food and beverage space, many of whom are looking for a sugar replacement that does not compromise the superb consumption experience offered by their products.” “We are excited to partner with Ambrosia to enhance their enzymatic innovation for the sugar replacement industry,” said Mervyn de Souza, Senior Director of Business Development at Ginkgo Bioworks. “Ambrosia Bio’s high-performance enzymes and its conjugated allulose production process have the potential to significantly reduce the cost associated with the mass production of allulose, paving the way to reduced-sugar products without compromising taste or other key sensory traits.” To learn more about Ginkgo’s work in this space, join us on June 30th from 10:00 - 11:00 am ET for our Functional Food Proteins with Microbial Expression Systems virtual event. About Ginkgo Bioworks About Ambrosia Forward-Looking Statements of Ginkgo Bioworks AMBROSIA CONTACT: GINKGO BIOWORKS INVESTOR CONTACT: GINKGO BIOWORKS MEDIA CONTACT:
View original content to download multimedia:https://www.prnewswire.com/news-releases/ambrosia-bio-leverages-ginkgo-enzyme-services-to-develop-a-more-scalable-enzymatic-process-for-allulose-301866416.html SOURCE Ginkgo Bioworks | ||
Company Codes: NYSE:DNA |