ROCKFORD, Ill. (June 25, 2010) — Thermo Fisher Scientific, the world leader in serving science, today announced the expansion of its isobaric tandem mass tags product line with the new Thermo Scientific Cysteine-Reactive Tandem Mass Tag (cysTMT) Reagents. The cysTMT® Reagents enable protein identification and quantitation through the selective labeling of cysteine-containing peptides from complex biological samples. The labeling system can be used in multiplex analysis of up to six different samples concurrently in an experiment.
The cysTMT Reagents label only free sulfhydryl groups on cysteine residues, in contrast to the amine-reactive TMT® Reagents. Labeled peptides are then enriched using the Thermo Scientific Immobilized Anti-TMT Antibody Resin. The cysTMT Reagents and Anti-TMT Resin are effective for reducing sample complexity, improving dynamic range and studying cysteine modifications. The cysTMTzero and cysTMTsixplex Reagents are used as isotopic “light” and “heavy” duplex tags for quantitation at the MS stage. These tags enable quantitation of protein expression changes in cell and tissue samples that might not be amenable to metabolic isotopic labeling strategies (e.g., SILAC).
For more information on the cysTMT Reagents and Anti-TMT Resin, visit www.thermoscientific.com/pierce or call +1-815-968-0747.
Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving science.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of more than $10 billion, we have approximately 35,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through two premier brands, Thermo Scientific and Fisher Scientific, which offer a unique combination of continuous technology development and the most convenient purchasing options. Our products and services help accelerate the pace of scientific discovery, and solve analytical challenges ranging from complex research to routine testing to field applications. Visit www.thermofisher.com.
