Crucell N.V. (CRXL) And National Institutes of Health (NIH) Sign US$27.6 Million Ebola Vaccine Manufacturing Contract

LEIDEN, Netherlands, April 14, 2005 (PRIMEZONE) -- Dutch biotechnology company Crucell N.V. (Euronext:CRXL) (Nasdaq:CRXL) announced today that it has signed a manufacturing contract with the Vaccine Research Center (VRC), part of the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH), for the manufacture of vaccines against Ebola infections. Under the terms of the contract, Crucell will manufacture up to ten batches of clinical material of the PER.C6(r)-based Ebola vaccine in its own manufacturing facility. These materials will be used for Phase I and early Phase II clinical studies in humans. Crucell will receive up to 21.4 million (US$ 27.6 million) from the VRC for the manufacturing of these clinical lots.

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