FOUNTAIN VALLEY, CALIFORNIA--(Marketwire - October 22, 2007) - Sutura, Inc. (“Sutura”) (OTCBB: SUTU), an innovative developer of minimally invasive vascular suturing devices, today announced the successful human use of the SuperStitch EL in three patients to deliver a suture to the septum that separates the left and right atriums of the heart. Dr Michael Mullen placed the sutures into the septum to close defects known as a Patent Foramen Ovale (PFO).