SCHOFIELD, Wis.--(BUSINESS WIRE)--PuraMed BioScience (OTC Bulletin Board: PMBS), a pharmaceutical company engaged in the development and marketing of a line of revolutionary, new, non-prescription medicines targeting major consumer health needs including the treatment of migraine headaches, insomnia and tension-type headaches, under the brand name LipiGesic™, announced today that it has completed production on its first direct response television commercial.