Billerica, Massachusetts—April 7, 2010—Millipore Corporation (NYSE: MIL), a leading provider of technologies, tools and services for the global life science industry, will introduce ChemiBrite™ Luminescent GPCR Reporter Frozen Cells at the Society for Biomolecular Sciences annual conference being held from April 11 to 15 in Phoenix, Arizona, USA. The new cells allow drug developers to expand their testing of popular G-protein coupled receptors (GPCRs).
Currently, 40% of all marketed drugs are targeted to GPCRs, indicating their therapeutic importance. However, because of the limitations of traditional fluorescent GPCR assays, many potentially efficacious compounds have never been tested as GPCR agonists or antagonists.
To overcome this challenge, drug developers are increasingly turning to chemiluminescent GPCR assays. ChemiBrite Frozen Cells offer a non-toxic luminescent readout, in contrast to fluorescence dye-based assays that can cause cell death over time. In addition, luminescent measurement is not affected by the interfering background “noise” produced by autofluorescent cells or compounds.
ChemiBrite Luminescent GPCR Reporter Cells are provided frozen in a convenient, Ready-To-Assay™ format, so they can be used immediately after thawing.
The cell lines are the latest addition to Millipore’s portfolio of GPCR profiling products and services, which includes ChemiScreen™ GPCR cell lines and the GPCRProfiler® service–the first outsourced cell-based functional assay service for GPCR profiling.
About Millipore
Millipore (NYSE: MIL) is a life science leader providing cutting-edge technologies, tools, and services for bioscience research and biopharmaceutical manufacturing. As a strategic partner, we collaborate with customers to confront the world’s challenging human health issues. From research to development to production, our scientific expertise and innovative solutions help customers tackle their most complex problems and achieve their goals. Millipore Corporation is an S&P 500 company with more than 5,900 employees worldwide. For more information, call 800-645-5476 or visit www.millipore.com.
