WINSTON-SALEM, N.C.--(BUSINESS WIRE)--Targacept, Inc. (NASDAQ: TRGT) announced today the completion of the sale of an additional 548,780 shares of its common stock upon the exercise in full of the over-allotment option granted to the underwriters of its previously-announced public offering. The net proceeds to Targacept from the sale of these additional shares, after deducting underwriting discounts and commissions and estimated offering expenses, are approximately $10.6 million, resulting in total net proceeds of the public offering to Targacept of approximately $80.8 million.