Ricerca Biosciences And The Bicoll Group Enter Significant Collaboration Agreement

Concord, OH, USA/Munich, Germany/ Shanghai, P.R. China – December 6, 2006 – Ricerca Biosciences, LLC and the Bicoll Group today announced the signing of a collaboration agreement. The agreement builds on a long-term relationship between the two companies.

Ricerca and Bicoll will combine their strengths in MedChem Services to offer innovative solutions that streamline drug discovery and development. With Ricerca’s network of business development representatives throughout the United States, a close interaction to clients can be secured. Additionally, Ricerca will leverage Bicoll’s medicinal chemistry and atural product chemistry technology for drug discovery to North American clients.

“We believe that the access to Bicoll’s unique natural product chemistry technology as well as its competence in supportive reporting and IP protection will further strengthen our broad portfolio as a successful solution provider for product and process development and testing services,” commented Thomas Bradshaw, Chief Executive Officer of Ricerca. “Bicoll’s strong and reliable MedChem Services, conducted in China, will allow us to provide our clients with additional valuable support in drug discovery.”

“Joining forces, Bicoll and Ricerca will be able to provide high medicinal, natural product, and custom synthetic chemistry services with a competitive price range to their clients,” stated Dr. Kai Lamottke, General Manager of Bicoll (Shanghai) Co. Ltd. “As a state-of-the-art R&D company for high-tech natural product chemistry and drug discovery, the Bicoll Group has experienced an intensive growth spurt over the past few years – with the strong marketing partnership of Ricerca within North America we will now be able to provide our services together not only to European pharmaceutical customers, but to clients worldwide.”

Ricerca Biosciences, LLC, located on a 46-acre site in Concord, Ohio, is a contract drug discovery and development company, offering extensive discovery and development services that improve the odds of converting drug leads to candidates, moving candidates over preclinical hurdles to IND filing. Ricerca also support clinical trials through GMP API manufacture and bioanalytical services.

Bicoll is a biopharmaceutical company specializing in high-tech natural product chemistry to identify novel small molecules for drug discovery and related innovative fields. The research focus is on making compounds from natural resources compatible with customers' screening systems for drug discovery and various other fields of application. Bicoll's advanced approach of property-based screening selects promising candidates early on and avoids investment in less promising compounds. Bicoll's products and additional services, like custom synthesis, are tailored to its customers' needs to accelerate the development process of new pharmaceuticals.

The Bicoll Group comprises two legal entities: Bicoll GmbH in Munich, Germany and, since 2001, Bicoll Biotechnology (Shanghai) Co. Ltd. in Zhangjiang Hi-Tech Park, P.R. China. Technology development, cooperation management and marketing are functions in Munich, while facilities for research and development are located in Shanghai.

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