WASHINGTON (Reuters) - Some children may have a genetic mutation that may predispose them to develop autism when exposed to mercury from fish or other sources, an environmental group said on Monday.
New research shows that some children may lack sufficient levels of glutathione, an amino acid involved in several cell processes, including the metabolism of toxins, the group said.
“When compared to normal, healthy children, autistic children showed a significant impairment in every one of five measurements of the body’s ability to maintain a healthy glutathione defense,” the Environmental Working Group said in its report.
“Reduced antioxidant defense may characterize a group of individuals who are demonstrably more sensitive to the effects of a range of toxic chemical exposures, and shed light on increasing rates of related learning and behavioral disorders.”
The group said the findings by former Food and Drug Administration senior research scientist Dr. Jill James, now of the University of Arkansas for Medical Sciences, reopened the debate on whether vaccines containing a mercury-based preservative called thimerosal may cause autism.
“The implications of these findings extend well beyond thimerosal and autism,” the report states.
Many studies have shown no link between routine immunizations and autism, including a report from an Institute of Medicine Committee earlier this year that reviewed the published research.
A member of the Institute of Medicine committee that wrote the report said the EWG report provided no strong evidence of any cause for autism.
“This is a very small piece in a very, very big puzzle,” said Dr. Steven Goodman of the Johns Hopkins School of Medicine in Baltimore.
“This doesn’t remotely establish what is cause and what is effect here,” Goodman added in a telephone interview.
“If we don’t have an infinite amount of money to study autism, which we don’t, we should be focusing on understanding the disease, understanding when the disease starts, genetic and environmental contributors, of which there could be many.”
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