FDA Signs Contract with Entelos, Inc. to Predict Cardiovascular Adverse Events

Foster City, CA, December 16, 2008 - Entelos, Inc. (LSE: ENTL), the leader in predictive disease simulation for pharmaceutical, health-care and consumer products applications, today announced that it has entered into an agreement with the U.S. Food and Drug Administration (FDA) to use the Entelos® Cardiovascular PhysioLab® to assess the cardiovascular safety and efficacy of a specific drug class and a set of drugs within that class. The compound class and specific set of drugs were not disclosed.