WATERTOWN, Mass.--(BUSINESS WIRE)--Tetraphase Pharmaceuticals, Inc., yesterday presented new clinical and preclinical data for its lead drug candidate, TP-434, which demonstrated the novel antibiotic as a once-daily intravenous (I.V.) monotherapy capable of treating multidrug-resistant gram-negative pathogens while also having potency and broad spectrum coverage of other serious and multidrug-resistant gram-positive pathogens. Additionally, Tetraphase presented new data that showed the potential for TP-434 to be effective in an oral formulation, which makes TP-434 ideally suited as a first-line IV antibiotic with oral step-down for severe and life-threatening bacterial infections. These data were presented in an oral session and in two poster sessions at the 2010 Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in Boston, MA, being held September 12-15. Tetraphase is a clinical stage biopharmaceutical company utilizing breakthrough synthetic chemistry technology to discover and develop next-generation antibiotics.
