CRANBURY, N.J., Dec. 1 /PRNewswire-FirstCall/ -- Palatin Technologies, Inc. today announced that the U.S. Patent and Trademark Office has issued U.S. Patent No. 7,622,440, titled “Cyclic Natriuretic Peptide Constructs.” The claims in the issued patent cover a family of cyclic compounds that bind to natriuretic peptide receptor A (NPRA), including PL-3994, Palatin’s lead heart failure drug candidate.
PL-3994 and the related family of cyclic compounds were discovered and developed by Palatin scientists and are solely owned by Palatin. In addition to this issued U.S. patent, Palatin has applications pending in selected countries outside the United States and additional U.S. applications covering related compounds.
PL-3994 incorporates a novel and proprietary amino acid mimetic developed by scientists at Palatin. PL-3994 has an extended half-life, with reduced affinity for natriuretic peptide clearance receptors and increased resistance to neutral endopeptidase, an endogenous enzyme that degrades natriuretic peptides. The result is a drug candidate with improved pharmacokinetic and pharmacodynamic properties.
About Palatin Technologies, Inc.
Palatin Technologies, Inc. is a biopharmaceutical company focused on discovering and developing targeted, receptor-specific small molecule and peptide therapeutics. Palatin’s strategy is to develop products and then form marketing collaborations with industry leaders in order to maximize their commercial potential. For additional information regarding Palatin, please visit Palatin Technologies’ website at www.palatin.com.
CONTACT: Investor Inquiries, Stephen T. Wills, CPA, MST, EVP-Operations /
Chief Financial Officer of Palatin Technologies, +1-609-495-2200,
info@palatin.com; or Media Inquiries, Carney Noensie, Vice President,
Investor Relations of Burns McClellan +1-212-213-0006, cnoensie@burnsmc.com
Web site: http://www.palatin.com/
