Inhibitors Of The Molecule PI3K Throw One Form Of Leukemia A CurveB-ALL, University of California, Irvine Study

ScienceDaily (Aug. 26, 2008) — Some cases of a form of leukemia known as pre–B cell acute lymphoblastic leukemia (pre–B-ALL) are caused by a genetic event that leads to the generation of a rogue chromosome known as the Philadelphia (Ph) chomosome, and individuals with Ph+ pre–B-ALL tend to have a poor outlook. As current treatments for Ph+ pre–B-ALL are not very effective, researchers are looking for new drugs to combat this disease.