Cardima, Inc. Announces Patent for INTELLITEMP(R) Energy Management Device

FREMONT, CA--(Marketwire - October 11, 2007) - Cardima, Inc. (OTCBB: CADM), developer of the REVELATION® Tx, REVELATION® T-Flex ablation microcatheters and INTELLITEMP® Energy Management Device, announces today that it received a new patent from the U.S. Patent and Trademark Office (U.S. Patent No. 7,252,664) for the Company’s commercially available product, the INTELLITEMP® Energy Management Device. This device is used to control the delivery of radio-frequency (RF) energy during ablation procedures in the electro-physiology and surgical markets. The feedback system incorporates both temperature and impedance from Cardima’s full line of ablation microcatheters and surgical probes. This patent reinforces the uniqueness of the INTELLITEMP’s modular architecture that controls RF energy delivery to any combination of up to 8 electrodes simultaneously along a linear ablation catheter or surgical probe. In comparison to standard “drag and burn” ablation technologies, simultaneous ablation through multiple electrodes of a Cardima linear ablation catheter or surgical probe controlled by the INTELLITEMP shortens procedure time. Furthermore, this process safely creates clean lesions that have penetrating depth, without gaps along the linear trajectory. The INTELLITEMP is marketed in the U.S.A. as part of the Cardima Surgical Ablation System, and CE Marked in the EU for both surgical and cardiac electro-physiology ablation applications.

MORE ON THIS TOPIC