Biotech’s New Cycle, JPM Deal Hype and Where Alpha Still Hides

In this episode of Denatured, Jennifer C. Smith-Parker speaks with RTW’s Rod Wong and Stephanie Sirota how shifting JPM deal timing masks record M&A potential; why oncology, obesity, psychedelics, and neuroscience are attracting fresh capital; and how “alpha stacking” shapes their investment edge in an age of chronic uncertainty. They cover topics discussed in RTW’s new book, “Innovation is the Best Medicine.”

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In this Denatured episode, Jennifer C. Smith-Parker talks with RTW’s Rod Wong and Stephanie Sirota about how changes in JPM deal timing may obscure a wave of record M&A activity; the renewed investor focus in previously overlooked therapeutic areas; and how their “alpha stacking” approach offers an investment edge. The conversation also draws on insights from RTW’s new book, “Innovation is the Best Medicine.”

Host

⁠Jennifer Smith-Parker⁠, Director of Insights, BioSpace

Guests

Roderick Wong, Managing Partner, Chief Investment Officer, RTW Investments

Stephanie Sirota, Partner, Chief Business Officer, RTW Investments

Disclaimer: The views expressed in this discussion by guests are their own and do not represent those of their organizations.

Jennifer C. Smith-Parker is Director of Insights at BioSpace. She has been been immersed for 20 years in healthcare, first as a journalist and editor before pivoting to corporate, brand, and product communications. A skilled storyteller, she is adept at creating diverse content across platforms and crafting narratives that drive engagement, strengthen reputation, and deliver measurable growth. You can reach her at Jennifer.Smith-Parker@BioSpace.com.
The BioSpace Insights teams performs research and analysis on industry trends for BioSpace and clients, producing industry reports, podcasts, events and articles.
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