LOS ANGELES--(BUSINESS WIRE)--Abraxis BioScience, Inc. (NASDAQ:ABBI), an integrated, global biopharmaceutical company, today announced that the company will begin enrollment in two Phase I/II clinical trials to investigate the use of nab™-docetaxel (ABI-008), an albumin-bound chemotherapeutic, for the treatment of hormone refractory prostate and metastatic breast cancer. Enrollment in the first study for hormone refractory prostate cancer is expected to begin in April 2007, with the second Phase I/II trial in metastatic breast cancer starting shortly thereafter in the second quarter of 2007. Both trials will be conducted at The University of Texas M. D. Anderson Cancer Center in Houston, Texas. Abraxis received FDA clearance for the nab-docetaxel investigational new drug (IND) application in January 2007. Nab-docetaxel is the second drug based on the company’s proprietary nanoparticle albumin-bound (nab™) technology to enter clinical development. ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin-bound), the first drug to utilize the nab technology platform, was approved by U.S. Food and Drug Administration for the treatment of metastatic breast cancer in January 2005.
