Protherics PLC Release: CytoFabTM Phase 2 Programme in Severe Sepsis Commenced by AstraZeneca PLC

London, UK; Brentwood, TN, US; 22 January 2008 - Protherics PLC (“Protherics” or the “Company”), the international biopharmaceutical company focused on critical care and cancer, today announces that AstraZeneca has treated the first patient in its expanded phase 2 programme of CytoFabTM in severe sepsis, an inflammatory condition resulting from uncontrolled infections.

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