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Clinical Catch-Up: November 4-8
11/11/2019
It was a busy week for clinical trial updates for the first week of November. Here’s a look. -
Genentech announced this morning that its experimental SMA drug risdiplam hit the mark in the second part of the pivotal SUNFISH study of patients with Type 2 and 3 of the disease.
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The World Anti-Microbial Resistance Congress 2019 was held November 7-8 in Washington, D.C.
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Lytix Biopharma announces a clinical collaboration agreement with Iovance Biotherapeutics, Inc. (NASDAQ: IOVA)
11/11/2019
Lytix Biopharma AS announces a clinical collaboration with the US-based company Iovance Biotherapeutics, Inc., a late-stage biotechnology company developing novel cancer immunotherapies based on tumor infiltrating lymphocyte technology, to evaluate Lytix`s first-in-class oncolytic peptide, LTX-315, in combination with Iovance`s autologous ready to infuse T cell therapy.
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Big Pharma Gaining Increased Interest in Fighting Cancer With Oncolytic Virus Therapies
11/11/2019
USA News Group – As the global oncology drug market is projected to grow at a rate of 7.6% CAGR to hit $176.5 billion by 2025, there's a growing interest within the big pharma sector to tap into the power of viruses to fight cancer.
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Qrons Extends Sponsored Research Agreement with Dartmouth College
11/11/2019
Qrons Inc. (OTCQB: QRON), an emerging biotechnology company developing advanced stem cell-synthetic hydrogel-based solutions for the treatment of traumatic brain injuries (TBIs) including concussions and penetrating injuries, today announced that it has extended the term of its Sponsored Research Agreement with Dartmouth College for an additional year with funding through July 14, 2020.
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Magenta Therapeutics Presents First Immune Reset Results with Antibody-Drug Conjugate Across Multiple Autoimmune Diseases at ACR
11/11/2019
Single dose of CD45-ADC shown to remove disease-causing cells and halt disease in models of multiple sclerosis, systemic sclerosis and inflammatory arthritis
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New Study Shows Promise in Treating More Patients with World’s Smallest Pacemaker
11/11/2019
Medtronic plc (NYSE:MDT) today announced results from the MARVEL 2 (Micra Atrial Tracking Using A Ventricular accELerometer) study showing that an investigational set of algorithms in the Micra™ Transcatheter Pacing System (TPS) significantly improves synchrony and cardiac function in patients with impaired electrical conduction between the chambers of the heart, called atrioventricular (AV) block
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Newly Published Research Demonstrates Ability of Hologic’s Assay to Detect Mycoplasma Genitalium, “the Silent Epidemic”
11/11/2019
First FDA-cleared test for this sexually transmitted bacterium can lead to earlier detection and appropriate treatment
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Every week there are numerous scientific studies published. Here’s a look at some of the more interesting ones.
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Could an immunosuppressant boost cognition in senior citizens? A recent animal study from the University of Texas Health Science Center at San Antonio suggests the possibility.
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prismCDX Implements Ultivue’s UltiMapper™ Platform for Standardized, Comprehensive Cancer Tissue Phenotypic Characterization
11/8/2019
prismCDX, a highly specialized contract research organization announced today the selection and adoption of the UltiMapper platform to broaden its offering of translational biomedical research services.
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New Data Presented at ACAAI 2019 Show Importance of Clinical History in Identifying AR101-Eligibile Patients for PALISADE Study without a Food Challenge
11/8/2019
Aimmune Therapeutics, Inc. (Nasdaq:AIMT), a biopharmaceutical company developing treatments for potentially life-threatening food allergies, today presented new data showing that a strong clinical history, in combination with evidence of peanut sensitization, is the optimal approach to identify peanut-allergic patients who are highly sensitive to peanut protein
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Lung Cancer Research Foundation Raises Awareness of Lung Cancer in Women
11/8/2019
In the United States, lung cancer claims more women's lives each year than breast, ovarian, and cervical cancers combined. In many countries around the world, it has become the leading cause of cancer death in women
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Data Showing Potential for Machine Learning to Advance Understanding of Nonalcoholic Steatohepatitis (NASH) Presented at the Liver Meeting® 2019
11/8/2019
Gilead Sciences, Inc. (Nasdaq: GILD) today announced new data from the company’s nonalcoholic steatohepatitis (NASH) research and development program, including studies evaluating machine learning approaches to the interpretation of liver histology, noninvasive tests (NITs) for the characterization and monitoring of disease severity, and novel therapies for the treatment of this disease.
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Exact Sciences Presents Data On Blood-Based Test For Detection Of Hepatocellular Carcinoma, Earns FDA Breakthrough Device Designation
11/8/2019
A new study of 443 patients by Exact Sciences Corp. and its collaborators demonstrated 80% sensitivity at 90% specificity with a novel combination of six blood-based biomarkers for the most common type of liver cancer, hepatocellular carcinoma (HCC)i
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New CRISPR-Cas9 design could improve therapies for HIV, sickle cell disease patients
11/8/2019
This modified design for the CRISPR gene editing tool could eventually improve therapies for HIV and sickle cell disease
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Atriva Therapeutics Reports Results of ATR-002 Phase I Clinical Trial
11/8/2019
A clinical Phase II safety and efficacy trial is planned for 2020 for the treatment of influenza, an indication with a very high unmet medical need
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Regenstrief playing major role in nationwide effort to improve care for dementia patients
11/8/2019
Brown University and Hebrew SeniorLife leading research incubator
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Through the use of cutting-edge gene sequencing, a team of researchers from Abbott Laboratories discovered a new strain of HIV, the first time a new subtype of HIV-1 has been identified in nearly 20 years.