IO Biotech, a clinical-stage biopharmaceutical company developing novel, immune modulating anti-cancer therapies, based on its proprietary T-win® technology, announces that the first patient has received the first dose in an international Phase I/II clinical trial studying the investigational candidate IO102 in combination with KEYTRUDA® (pembrolizumab) for patients with non-small cell lung cancer (NSCLC) – NCT03562871.
COPENHAGEN, Denmark /PRNewswire/ -- IO Biotech, a clinical-stage biopharmaceutical company developing novel, immune modulating anti-cancer therapies, based on its proprietary T-win® technology, announces that the first patient has received the first dose in an international Phase I/II clinical trial studying the investigational candidate IO102 in combination with KEYTRUDA® (pembrolizumab) for patients with non-small cell lung cancer (NSCLC) – NCT03562871. "The enrolment of the first patient in our Phase I/II trial for NSCLC represents a major milestone for IO Biotech, and we are excited that our global trial is now active and recruiting patients. The first patient is now being treated in a first-line treatment setting of metastatic non-small cell lung cancer," said Eva Ehrnrooth, MD, PhD, Chief Medical Officer of IO Biotech. "Through this trial, we expect to get a diverse set of clinical data. This will enable us to explore the potential of IO102 when added to the current standard of care." IO Biotech's lead candidate, IO102, is an IDO-derived immune modulating therapy with a dual mode of action - killing both cancer and immune-suppressive cells. IO Biotech's IDO-derived immune modulating therapies have previously shown both a favorable safety profile and promising anti-tumor activity in a first-in man trial of heavily pre-treated patients with NSCLC. The IO102-012/KN-764 trial is part of a collaborative agreement with Merck & Co., Inc., Kenilworth, NJ, USA (known as MSD outside the US and Canada). The clinical trial will be sponsored by IO Biotech. IO Biotech has retained global commercial rights to IO102. About the study The clinical trial will be sponsored by IO Biotech while MSD will supply the trial with KEYTRUDA®. The rights to the study results will be shared. IO Biotech will maintain global commercial rights to IO102. About IO Biotech About T-win technology platform For further information, please visit: www.iobiotech.com. About NSCLC KEYTRUDA® is a registered trademark of Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA. Contacts
SOURCE IO Biotech |