GlaxoSmithKline Appoints Zhi Hong to Head Infectious-Diseases Research Center

PHILADELPHIA and LONDON, March 29 /PRNewswire-FirstCall/ -- GlaxoSmithKline announces the appointment of Zhi Hong, Ph.D., to lead a newly organized research unit dedicated to discovering therapies for infectious diseases, effective 23 April.

Currently, Dr. Hong is Executive Vice President and Chief Scientific Officer of Ardea Biosciences, Inc., a San Diego, California, biopharmaceutical company focused on the discovery and development of targeted small molecule drugs to treat viral diseases, cancer, and inflammation. He earlier served as Vice President and Head of Research at Valeant Pharmaceuticals International, where he built up the Discovery group to eventually lead the entire Research group of approximately 120 staff to support activities from target selection through Phase II clinical studies, with an emphasis on infectious diseases. Previously, he worked in various research and management roles at Schering- Plough Research Institute.

Dr. Hong is an inventor who holds numerous patents and an author of more than 100 research papers, the majority of them in the field of infectious diseases.

“The appointment of a researcher of Dr. Hong’s stature reflects GSK’s continuing commitment to combat such threats as HIV/AIDS, viral hepatitis, and bacterial resistance to currently marketed antibiotics,” said Patrick Vallance, M.D., Senior Vice President, Drug Discovery, GSK Research & Development. “We have a long tradition of innovation in discovering and developing therapies for infectious diseases, and we intend to build on that tradition.”

At GSK, Dr. Hong will head the Infectious Diseases Center of Excellence for Drug Discovery (ID CEDD). This CEDD is being formed to integrate and better coordinate the mid-stage infectious-diseases research and development under way in the R&D organization. It will focus on building an innovative pipeline through both internal efforts and extensive alliances with other companies and research institutions. Additionally, the ID CEDD includes the GSK research center in Tres Cantos, Spain, which is dedicated to therapies for diseases prevalent in the developing world, such as malaria and tuberculosis.

GSK R&D comprises nine CEDDs, organized by therapeutic area or technology, to manage the progression of compounds from therapeutic hypothesis to clinical proof of concept. While drawing from the broader resources of the R&D organization, the CEDDs bridge the conventional gap between discovery and development, bringing scientists and physicians together in groups the size of small biotechnology companies.

GlaxoSmithKline -- one of the world’s leading research-based pharmaceutical and healthcare companies -- is committed to improving the quality of human life by enabling people to do more, feel better and live longer. Enquiries: UK Media enquiries: Philip Thomson (020) 8047 5502 Alice Hunt (020) 8047 5502 Gwenan White (020) 8047 5502 US Media enquiries: Nancy Pekarek (215) 751 7709 Mary Anne Rhyne (919) 483 2839 European Analyst/Investor enquiries: Anita Kidgell (020) 8047 5542 David Mawdsley (020) 8047 5564 Sally Ferguson (020) 8047 5543 US Analyst/ Investor enquiries: Frank Murdolo (215) 751 7002 Tom Curry (215) 751 5419

GlaxoSmithKline

CONTACT: UK Media: Philip Thomson, (020) 8047 5502, Alice Hunt, (020) 80475502, or Gwenan White, (020) 8047 5502; US Media: Nancy Pekarek,+1-215-751-7709, or Mary Anne Rhyne, +1-919-483-2839; European Analysts-Investors: Anita Kidgell, (020) 8047 5542, David Mawdsley, (020) 8047 5564,or Sally Ferguson (020) 8047 5543; US Analysts-Investors: Frank Murdolo,+1-215-751-7002, or Tom Curry, +1-215-751-5419, all for GlaxoSmithKline

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