Discovery Partners International Inc. Reports Second Quarter 2006 Results

SAN DIEGO, Aug. 9 /PRNewswire-FirstCall/ -- Discovery Partners International, Inc. today announced unaudited financial results for the three and six month periods ended June 30, 2006.

Following the Company’s sale of all of the stock of its operating subsidiaries and all of its material operating assets pursuant to a stock and asset purchase agreement with Galapagos NV and Biofocus Inc., a subsidiary of Galapagos NV, and the sale of the instrumentation product lines in 2005, the Company no longer reports any revenue nor associated expense, nor any historical operating results related to its operating activities. These results are reported as discontinued operations. The Company’s results from continuing operations arise solely from general and administrative and other expenses related to its corporate activities and investment income on its marketable securities portfolio.

Net loss from continuing operations for the three months ended June 30, 2006 was $3.2 million, or $0.12 per share, compared to a net loss of $2.2 million, or $0.08 per share, for the same period in 2005. Net loss from continuing operations for the six months ended June 30, 2006 was $5.3 million, or $0.20 per share, compared to a net loss of $4.9 million, or $0.19 per share, for the same period in 2005.

Selling, general and administrative costs for the second quarter of 2006 were $4.1 million, up from $2.6 million in the second quarter of 2005 due to costs related to the Company’s strategic initiatives, which more than offset savings from lower staffing levels. Selling, general and administrative costs for the first half of 2006 were $7.0 million, up from $5.7 million in the first half of 2005 due to costs related to the Company’s strategic initiatives, which more than offset the absence of severance payments to our former COO and savings from lower staffing levels.

Investment income for the three and six months ended June 30, 2006 were $0.9 million and $1.8 million, respectively, up from $0.4 million and $0.9 million, respectively, for the same periods in 2005 due to higher yields on the Company’s investment portfolio.

Net loss from discontinued operations for the three months ended June 30, 2006 was $1.2 million, or $0.05 per share, compared to net income of $0.8 million, or $0.03 per share, for the same period in 2005. Net loss from discontinued operations for the six months ended June 30, 2006 was $8.3 million, or $0.31 per share, compared to a net loss of $1.0 million, or $0.04 per share, for the same period in 2005. The increased loss for both periods resulted primarily from a significant reduction in revenue generated from the discontinued operations in 2006 versus 2005.

Cash, cash equivalents and short-term investments at June 30, 2006 were $75.4 million, a decrease of $4.7 million from the balance at March 31, 2006 due primarily to the net loss. This cash number does not reflect the $5.4 million received from the sale of our operational assets to Galapagos NV in early July.

“During the second quarter of 2006, Discovery Partners announced both the merger with Infinity Pharmaceuticals, and the sale of our drug discovery business to Galapagos NV for $5.4 million in cash,” said Michael C. Venuti, Ph.D., Acting Chief Executive Officer of Discovery Partners. “Importantly, we were able to complete the sale to Galapagos NV without incurring either major severance or shutdown costs. The combination of these strategic initiatives is intended to afford our shareholders the opportunity to participate in the growth associated with the cancer drug development portfolio of Infinity. The date for the special meeting Discovery Partners’ shareholders to vote on the Infinity merger and related matters is September 12, 2006,” concluded Venuti.

About Discovery Partners International, Inc.

Discovery Partners International, Inc. (DPI) has entered into a merger agreement with Infinity pursuant to which Infinity will merge with and into a wholly owned subsidiary of Discovery Partners, with Infinity as the surviving corporation, becoming a wholly owned subsidiary of Discovery Partners. In connection with the merger, Discovery Partners recently completed the sale of all of the stock of its operating subsidiaries and all of its material operating assets pursuant to a stock and asset purchase agreement with Galapagos NV. and Biofocus Inc., a subsidiary of Galapagos NV. Discovery Partners’ only remaining material assets following that sale are its cash, cash equivalents and short-term investments, its listing on the NASDAQ Global Market and its merger agreement with Infinity. The terms of the Infinity merger agreement and the stock and asset purchase agreement with Galapagos and Biofocus, and the remaining assets of Discovery Partners following the closing of the transactions described in such agreements are contained in Discovery Partners’ filings with the Securities and Exchange Commission and are available on the Company’s web site at http://www.discoverypartners.com.

About Infinity Pharmaceuticals, Inc.

Infinity is an innovative cancer drug discovery and development company that leverages its strength in small molecule technologies to bring important new medicines to patients. For more information on Infinity Pharmaceuticals, including a copy of this release in the Media Room, please visit the company’s web site at http://www.ipi.com.

Additional Information about the Merger and Where to Find It

In connection with the proposed merger transaction with Infinity, on August 7, 2006 an amended registration statement was filed with and has been declared effective by the Securities and Exchange Commission that contains a proxy statement/prospectus. Investors and security holders of Discovery Partners and Infinity are urged to read the proxy statement/prospectus (including any amendments or supplements to the proxy statement/prospectus) regarding the proposed transaction because it contains important information about Discovery Partners, Infinity and the proposed transaction. Discovery Partners’s stockholders can obtain a free copy of the proxy statement/prospectus, as well as other filings containing information about Discovery Partners and Infinity, without charge, at the SEC’s Internet site (http://www.sec.gov). Copies of the proxy statement/prospectus can also be obtained, without charge, by directing a request to Discovery Partners International, Inc., 9640 Towne Centre Drive, San Diego, CA 92121, Attention: Investor Relations, Telephone: (858) 455-8600.

Participants in the Solicitation

Discovery Partners and its directors and executive officers and Infinity and its directors and executive officers may be deemed to be participants in the solicitation of proxies from the stockholders of Discovery Partners in connection with the proposed transaction. Information regarding the special interests of these directors and executive officers in the merger transaction is included in the proxy statement/prospectus referred to above. Additional information regarding the directors and executive officers of Discovery Partners is also included in Discovery Partners’s proxy statement for its 2006 Annual Meeting of Stockholders, which was filed with the SEC on April 6, 2006. This document is available free of charge at the SEC’s web site (http://www.sec.gov) and from Discovery Partners’s Investor Relations at the address listed above.

Forward-Looking Statements

This release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include statements regarding the proposed transaction and, the growth associated with Infinity’s drug portfolio. Factors that may cause actual results to differ materially include the risk that Discovery Partners and Infinity may not be able to complete the proposed transaction, the risk that Infinity product candidates that appeared promising in early research and clinical trials do not demonstrate safety and/or efficacy in larger-scale or later clinical trials, the risk that Infinity will not obtain approval to market its products, the risks associated with reliance on outside financing to meet capital requirements, and the risks associated with reliance on collaborative partners for further clinical trials, development and commercialization of product candidates. You are urged to consider statements that include the words “may,” “will,” “would,” “could,” “should,” “believes,” “estimates,” “projects,” “potential,” “expects,” “plans,” “anticipates,” “intends,” “continues,” “forecast,” “designed,” “goal,” or the negative of those words or other comparable words to be uncertain and forward-looking. These factors and others are more fully discussed in Discovery Partners’s periodic reports and other filings with the SEC.

Any forward-looking statements are made pursuant to Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, and, as such, speak only as of the date made. Discovery Partners undertakes no obligation to publicly update any forward-looking statements, whether as a result of new information, future events or otherwise.

DISCOVERY PARTNERS INTERNATIONAL, INC. Selected Consolidated Financial Data (In Thousands, Except Per Share Amounts) Consolidated Statements Three Months Ended Six Months Ended of Operations June 30 June 30 2006 2005 2006 2005 (Unaudited) (Unaudited) Operating expenses: Selling, general and administrative 4,124 2,619 7,000 5,742 Restructuring -- -- 22 -- Total operating expenses 4,124 2,619 7,022 5,742 Loss from continuing operations (4,124) (2,619) (7,022) (5,742) Interest income, net 896 413 1,752 878 Foreign currency transaction gain (loss), net -- -- (11) (4) Other income, net (9) (3) 4 -- Loss from continuing operations before income taxes (3,237) (2,209) (5,277) (4,868) Income tax refund -- (11) -- -- Net loss from continuing operations $(3,237) $(2,198) $(5,277) $(4,868) Discontinued operations: Gain on sale of discontinued operations -- -- 165 -- Income (loss) from discontinued operations (1,177) 830 (8,341) (1,048) Net loss $(4,414) $(1,368) $(13,453) $(5,916) Basic and diluted: Continuing operations $(0.12) $(0.08) $(0.20) $(0.19) Discontinued operations $(0.05) $0.03 $(0.31) $(0.04) Net loss per share $(0.17) $(0.05) $(0.51) $(0.23) Weighted average shares outstanding: Basic and diluted: 26,116 25,853 26,114 25,848 Summary Balance Sheets June 30, December 31, (In Thousands) 2006 2005 (Unaudited) Assets Current assets: Cash and cash equivalents $25,652 $24,231 Short-term investments, net 49,783 59,255 Prepaid and other current assets 1,715 1,050 Assets of discontinued operations 10,541 16,618 Total current assets 87,691 101,154 Restricted cash -- 1,061 Other assets, net -- 64 Total assets $87,691 $102,279 Liabilities and Stockholders’ Equity Current liabilities: Accounts payable and accrued expenses $568 $742 Accrued compensation 495 421 Liabilities of discontinued operations 4,042 6,042 Total current liabilities 5,105 7,205 Stockholders’ Equity: Common stock 26 26 Common stock issuable -- 1,597 Treasury stock (1,037) (1,037) Additional paid-in-capital 210,690 209,237 Deferred compensation -- (919) Accumulated other comprehensive income 253 64 Accumulated deficit (127,346) (113,893) Total stockholders’ equity 82,586 95,075 Total liabilities and stockholders’ equity $87,691 $102,279 Summary Statement of Cash Flows Six Months Ended (In Thousands) June 30, 2006 (Unaudited) Net Loss $(13,453) Adjustments to reconcile net loss to cash and cash equivalents used in operating activities: Gain on sale of discontinued operations (165) Depreciation and amortization (27) Stock based compensation 751 Restructuring expense 22 Realized loss on investments (4) Change in operating assets and liabilities: Other current assets 515 Accounts payable and accrued expenses (168) Net cash used in operating activities (12,529) Net cash provided by operating activities of discontinued operations 5,519 Investing activities: Proceeds from sale of division 165 Proceeds from sales and maturity of short-term investments, net of purchases 9,498 Net cash provided by investing activities 9,663 Net cash used in investing activities of discontinued operations (1,372) Financing activities: Net proceeds from issuance of common stock 24 Net cash provided by financing activities 24 Effect of exchange rate changes 116 Net increase in cash and cash equivalents 1,421 Cash and cash equivalents at beginning of period 24,231 Cash and cash equivalents at end of period $25,652

Discovery Partners International, Inc.

CONTACT: Michael C. Venuti, Ph.D., Acting Chief Executive Officer,+1-858-455-8600, ir@discoverypartners.com, or Craig Kussman, ChiefFinancial Officer, +1-858-228-4113, both of Discovery PartnersInternational

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