Diffinity Genomics(TM) and Sigma-Aldrich Corporation Sign Global Distribution Agreement for RapidTip(R)

Rochester, NY – November 29, 2011 -- Diffinity Genomics™, Inc. a biotechnology company focused on providing faster, simpler nucleic acid purification products for life science researchers, announced they have signed a non-exclusive global distribution agreement with Sigma-Aldrich® to distribute Diffinity’s PCR purification product, the Diffinity RapidTip®. The distribution agreement will help expand the availability of Diffinity’s RapidTip brand products to life science researchers worldwide who desire a faster, easier way to purify their PCR products.

Diffinity Genomics has developed technology that can be used to remove impurities from a wide range of nucleic acid samples based on different molecular properties, such as structure (e.g., single vs. double-stranded DNA) or size (e.g., short vs. long DNA sequences). The company’s current product line, the Diffinity RapidTip for PCR Purification, decreases the time of PCR purification to approximately one minute, using just a standard pipettor and one Diffinity RapidTip pipette tip, for use in downstream applications such as Sanger sequencing, SNP analysis, and microarray printing. No additional reagents, equipment, or consumables are needed and waste is limited to just the single, “functionalized” pipette tip. The RapidTip appreciably reduces the time and effort by laboratory personnel to purify samples enabling them to spend more time on higher value-added activities, such as analysis of results. The technology is also easily adaptable for use with virtually any manual, bench top, or automated laboratory fluid handling system.

"Our focus has been on expanding Diffinity's products around the world. Sigma-Aldrich is a well-respected, major life science reagent supplier with a commitment to providing innovative products,” said Robin Hodownes, VP, Sales & Marketing, Diffinity Genomics. "The RapidTip has been making encouraging gains with customers around the world and we’re excited about the synergies that are available from our new agreement and the opportunity to better serve the needs of this growing market with current and future purification products."

Diffinity also has non-exclusive distribution agreements with strong regional partners in 16 countries in North America, Australia, Europe, and Asia. See www.diffinitygenomics.com for more information.

About Diffinity Genomics, Inc.:

Diffinity Genomics is a Rochester, NY-based company that is selling products to life science researchers for rapid and simple nucleic acid isolation & analysis based on its proprietary DiffinityTM technology, starting with the Diffinity RapidTip for PCR purification. Diffinity technology is based upon the ability to configure surfaces to preferentially adsorb and simultaneously repel different types of nucleic acids. The technology was developed in collaboration with the University of Rochester, Rochester, NY and scale-up was supported by a series of government grants. For more information about Diffinity Genomics, please visit its website at www.diffinitygenomics.com. These products are intended for life science research use only.

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Our biochemical and organic chemical products and kits are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development, and as key components in pharmaceutical, diagnostic and other high technology manufacturing. We have customers in life science companies, university and government institutions, hospitals and in industry. Over one million scientists and technologists use our products. Sigma-Aldrich operates in 40 countries and has over 8,300 employees providing excellent service worldwide. We are committed to accelerating our Customers' success through leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit our award winning web site at www.sigma-aldrich.com.

Safe Harbor Statement

This news release contains forward-looking statements related to future growth and earnings opportunities. Such statements are based upon certain assumptions and assessments made by management of companies mentioned in this press release in light of current conditions, expected future developments and other factors they believe to be appropriate. Actual results may differ as a result of factors over which the company has no control.

Diffinity, Diffinity Genomics, and RapidTip are trademarks or registered trademarks of Diffinity Genomics, Inc. Sigma-Aldrich is a registered trademark of Sigma-Aldrich Co. LLC.

Contact:

Robin Hodownes

VP, Sales & Marketing

Diffinity Genomics, Inc.

585-272-8141

rhodownes@diffinitygenomics.com

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