Gene Editing Market Size Worth USD 15.79 Billion By 2027 | Emergen Research

The global gene editing Market is projected to reach USD 15.79 billion by 2027, according to a recent report by Emergen Research. The market is expected to grow at a CAGR of 17.2% over the forecast period (2020-2027). The growing demand for personalized medicine and the increasing number of research and development activities in the field of gene therapy are some of the major factors driving the growth of this market. Additionally, the rising incidence of genetic disorders and the growing government support for gene therapy research are expected to contribute to market growth. However, the high cost of gene therapy and the ethical concerns associated with gene editing are some of the major factors restraining the growth of this market.

The use of the technology for malady wipeout has opened up new avenues for this technology. For instance, in September 2019, scientists from the University of Texas MD Anderson Cancer Center and Baylor College of Medicine announced that they had edited the genes of immune cells outside the human body and then transplanted them into patients with acute myeloid leukemia (AML), a cancer of the blood and bone marrow. The treatment resulted in the remission of cancer in three out of four patients. Moreover, according to the U.S. National Library of Medicine, around 21,380 people are expected to be diagnosed with AML in 2020 in the U.S. alone. Such an increase in the incidences of blood cancer is expected to drive the market for gene editing.

In order to improve over current treatment choices for various heritable diseases and to target and destroy cancer cells, scientists have been working on gene editing for a number of years now. With the help of new technologies, this process is getting more precise and efficient. As a result, the market for gene editing is expected to grow significantly in the next few years.

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Moreover, technological advancements with relevance to the event of novel vectors and instruments for gene modifying are likely to create huge opportunities in the coming years. For instance, in March 2019, Sangamo Therapeutics (US) initiated a phase III clinical study of SB-913 in Huntington’s disease and MPS IIIA. This study is based on zinc finger nuclease (ZFN) technology platform and is the first clinical study to assess the in vivo efficacy of ZFN-mediated gene editing in patients.

Some Key Highlights from the Report

• The CRISPR-Cas9 technology segment is expected to hold the largest market share over the forecast period. CRISPR-Cas9 is a type of gene-editing technology that can be used to alter DNA and genome sequencing. This technology helps in modifying genes and correcting genetic defects. Additionally, this technology can be used to treat various diseases, such as cancer, AIDS, and Huntington's disease. Moreover, the CRISPR-Cas9 technology is less expensive and more efficient as compared to other gene-editing technologies, such as ZFNs and TALENs.
• The vector delivery segment is expected to grow at the fastest CAGR over the forecast period. The vector delivery segment includes viral and non-viral vectors. Viral vectors are used for the delivery of CRISPR-Cas9 system into cells. These vectors can be derived from lentiviruses, adenoviruses, adeno-associated viruses, and others. Lentiviral vectors are commonly used for the delivery of CRISPR-Cas9 system into cells, as they can infect both dividing and non-dividing cells. Adenoviral vectors are also used for the delivery of CRISPR-Cas9 system into cells; however, they are less efficient as compared to lentiviral vectors.
• The in vivo segment is expected to grow at the fastest CAGR over the forecast period. The in vivo segment includes the delivery of CRISPR-Cas9 system into cells inside the human body. This method is used for the treatment of various diseases, such as cancer, AIDS, and Huntington's disease. Additionally, this method is less expensive and more efficient as compared to other gene-editing technologies, such as ZFNs and TALENs.
• The research institutes segment is expected to hold the largest market share over the forecast period. The research institutes segment includes academic research institutes and government research institutes. The academic research institutes segment comprises universities and colleges that are engaged in gene-editing research. The government research institutes segment comprises government organizations that are engaged in gene-editing research.
• The North America region is expected to hold the largest market share over the forecast period. The North American region comprises the U.S., Canada, and Mexico. The presence of a large number of biotechnology and pharmaceutical companies in this region is one of the major factors driving the growth of the market in this region. Additionally, the presence of a large number of research institutes in this region is another factor driving the growth of the market.
• Key participants embrace Cibus, Recombinetics, Inc, Merck KGaA, Sangamo, exactitude Biosciences and Editas medication among others.

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For the purpose of this report, Emergen Research has segmented into the global gene editing Market on the basis of technology, end user, applications and region:

Technology Outlook (Revenue, USD Billion; 2017-2027)

• • (CRISPR)/Cas9
  • TALENS/MegaTALs
  • ZFN
  • ANTISENSE
  • Other Technologies

Applications Outlook (Revenue, USD Billion; 2017-2027)

• • Cell Line Engineering
  • Animal Genetic Engineering
  • Plant Genetic Engineering
  • Diagnostic Applications
  • Drug Discovery and Development

End Users Outlook (Revenue, USD Billion; 2017-2027)

• • Biotechnology and Pharmaceutical Companies
  • Academic and Government Research Institutes
  • Contract Research Organizations (CROs)

Regional Outlook (Revenue: USD Billion; Volume: Million Tons; 2017-2027)

• • North America
    1. U.S.
    2. Canada
    3. Mexico
  • Europe
    1. UK
    2. Germany
    3. France
    4. BENELUX
    5. Rest of Europe
  • Asia Pacific
    1. China
    2. Japan
    3. South Korea
    4. Rest of APAC
  • Latin America
    1. Brazil
    2. Rest of LATAM
  • MEA
    1. Saudi Arabia
    2. UAE
    3. Rest of MEA

 

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