Addex Pharmaceuticals First Half 2009 Financial Results Tuesday, July 28

GENEVA, SWITZERLAND--(Marketwire - July 23, 2009) -

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Addex Pharmaceuticals Ltd. (SWISS: ADXN) will discuss its financial results for the first half of 2009 and reiterate the status of its pipeline during a teleconference and webcast for investors, analysts and the media on Tuesday, July 28 at 16:00 CEST. Addex updated its pipeline status at its R&D Day on July 16. The slides and recorded webcasts from the R&D Day are available at www.addexpharma.com.

Title: Addex First Half 2009 Financial Results Conference Call

Date:            28 July 2008
Time:            16:00 CEST
Dial-in numbers: +41 91 610 56 00  (Europe)
                 +44 207 107 0611  (UK)
                 +1 866 291 4166   (USA)

The live webcast and slides, as well as the webcast replay and transcript, will be available at www.addexpharma.com.

Addex Pharmaceuticals (www.addexpharma.com) discovers and develops allosteric modulators for human health. Allosteric modulators are a different kind of orally available small molecule therapeutic agent, which we believe will offer a competitive advantage over classical drugs. Our lead allosteric modulator product, ADX10059, has achieved clinical proof of concept and is in Phase IIb testing in two indications. Phase IIb data for ADX10059 to treat gastroesophageal reflux disease (GERD) are expected in the fourth quarter of 2009. Phase IIb data for ADX10059 as a migraine prevention therapy in patients with frequent migraine are expected in the first quarter of 2010. ADX10059 is a first-in-class mGluR5 inhibitor, a therapeutic strategy that also is being pursued in multiple indications by large pharma competitors.

Our products and technology already have proven their value through our relationships with four of the top 10 pharmaceutical companies in the world. Specifically, under an agreement with Ortho-McNeil-Janssen Inc., a Johnson & Johnson company, ADX71149, a positive allosteric modulator (PAM) of mGluR2 with potential for the treatment of schizophrenia and anxiety, is undergoing Phase I clinical testing. Under two separate agreements with Merck & Co., Inc., we are developing mGluR4 PAM and mGluR5 PAM as drugs to treat Parkinson's disease and schizophrenia, respectively. In addition, GlaxoSmithKline and Roche have made equity investments in Addex.

Disclaimer: The foregoing release may contain forward-looking statements that can be identified by terminology such as "not approvable", "continue", "believes", "believe", "will", "remained open to exploring", "would", "could", or similar expressions, or by express or implied discussions regarding Addex Pharmaceuticals Ltd, its business, the potential approval of its products by regulatory authorities, or regarding potential future revenues from such products. Such forward-looking statements reflect the current views of Addex Pharmaceuticals Ltd regarding future events, future economic performance or prospects, and, by their very nature, involve inherent risks and uncertainties, both general and specific, whether known or unknown, and/or any other factor that may materially differ from the plans, objectives, expectations, estimates and intentions expressed or implied in such forward-looking statements. Such may in particular cause actual results with allosteric modulators of mGluR2, mGluR4, mGluR5, mGluR7 or other therapeutic targets to be materially different from any future results, performance or achievements expressed or implied by such statements. There can be no guarantee that allosteric modulators of mGluR2, mGluR4, mGluR5, mGluR7 will be approved for sale in any market or by any regulatory authority. Nor can there be any guarantee that allosteric modulators of mGluR2, mGluR4, mGluR5, mGluR7 or other therapeutic targets will achieve any particular levels of revenue (if any) in the future. In particular, management's expectations regarding allosteric modulators of mGluR2, mGluR4, mGluR5, mGluR7 or other therapeutic targets could be affected by, among other things, unexpected actions by our partners, unexpected regulatory actions or delays or government regulation generally; unexpected clinical trial results, including unexpected new clinical data and unexpected additional analysis of existing clinical data; competition in general; government, industry and general public pricing pressures; the company's ability to obtain or maintain patent or other proprietary intellectual property protection. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those anticipated, believed, estimated or expected. Addex Pharmaceuticals Ltd is providing the information in this press release as of this date and does not undertake any obligation to update any forward-looking statements contained in this press release as a result of new information, future events or otherwise, except as may be required by applicable laws.