Researchers are closer to understanding why humans differ so greatly from chimpanzees in the way they look, behave, think, and fight off disease, despite having genes that are nearly 99% identical. Innovative research from the University of Toronto’s Centre for Cellular and Biomolecular Research has uncovered potential new explanations for these glaring differences. In comparing brain and heart tissue from humans and chimpanzees, U of T Professor Benjamin Blencowe and his team, including graduate student researcher John Calarco, have discovered significant differences in the way genetic material is spliced to create proteins.