Rosetta Genomics Ltd. and Collaborators to Present Data at American Society of Clinical Oncology 2011

PHILADELPHIA, PA and REHOVOT, ISRAEL--(Marketwire - May 23, 2011) - Rosetta Genomics (NASDAQ: ROSG), a leading developer and provider of microRNA-based molecular diagnostic tests, today announced that data from several studies demonstrating the clinical utility of the Company’s miRview® products to identify and classify a variety of cancers will be presented at the American Society of Clinical Oncology (ASCO) 2011 Annual Meeting taking place at the McCormick Place Convention Center in Chicago from June 3-7, 2011.

A study demonstrating the ability of miRview® lung to classify lung cancer in a poster entitled “New microRNA-based diagnostic test for lung cancer classification” will be presented at:

 Session: Tumor Biology Type: Poster Discussion Session Date/Time: Saturday, June 4, from 2:00 p.m. to 6:00 p.m. Location: McCormick Place S103, Poster Board #23 

A study highlighting the clinical utility of the Company’s miRview® mets2 to identify the tissue of origin in Cancer of Unknown Primary patients in a poster entitled “A second generation microRNA-based assay for diagnosing tumor tissue origin” will be presented at:

 Session: Tumor Biology Type: General Poster Session Date/Time: Monday, June 6, from 8:00 a.m. to 12:00 p.m. Location: McCormick Place Hall A, Poster Board #25B 

A study demonstrating the clinical utility of the Company’s miRview® kidney to classify kidney tumor types in a poster entitled “A microRNA-based diagnostic test for kidney tumor classification” will be presented at:

 Session: Tumor Biology Type: General Poster Session Date/Time: Monday, June 6, from 8:00 a.m. to 12:00 p.m. Location: McCormick Place Hall A, Poster Board #26B 

Each of the posters will be presented by Dr. Ayelet Chajut, Rosetta Genomics’ Executive Vice President, R&D, Head of Molecular Biology.

“We are especially pleased to be presenting this growing body of clinical data in support of the clinical utility of our miRview® diagnostic tests to accurately identify and classify various cancers at the prestigious ASCO conference. We recently launched our first company-led commercialization efforts in the U.S., and these data enhance the visibility of our miRview® diagnostics before an audience of the world’s leading oncologists,” commented Kenneth A. Berlin, President and Chief Executive Officer of Rosetta Genomics. “These data also enhance our commercial efforts by providing our sales team with the clinical support needed for widespread adoption of our miRview diagnostics in oncology.”

About miRview® Products
miRview® are a series of microRNA-based diagnostic products offered by Rosetta Genomics. miRview® mets and miRview® mets2 accurately identify the primary tumor site in metastatic cancer and CUP. miRview® squamous accurately identifies the squamous subtype of non-small cell lung cancer, which carries an increased risk of severe or fatal internal bleeding and poor response to treatment for certain therapies. miRview® meso diagnoses mesothelioma, a cancer connected to asbestos exposure. miRview® tests are designed to provide objective diagnostic data; it is the treating physician’s responsibility to diagnose and administer the appropriate treatment. In the U.S. alone, Rosetta Genomics estimates that approximately 200,000 patients a year may benefit from the miRview® mets and miRview® mets2 test, 60,000 from miRview® squamous and 60,000 from miRview® meso. The Company’s tests are offered directly by Rosetta Genomics in the U.S., and through distributors around the globe. For more information, please visit www.mirviewdx.com. Parties interested in ordering the test can contact Rosetta Genomics at (215) 382-9000 ext. 309.

About microRNAs
microRNAs (miRNAs) are recently discovered, small RNAs that act as master regulators of protein synthesis, and have been shown to be highly effective biomarkers. The unique advantage of microRNAs as biomarkers lies in their high tissue specificity, and their exceptional stability in the most routine preservation methods for biopsies, including Formalin Fixed Paraffin Embedded (FFPE) block tissue and fine needle aspirate (FNA) cell blocks. It has been suggested that their small size (19 to 21 nucleotides) enables them to remain intact in FFPE blocks, as opposed to messenger RNA (mRNA), which tends to degrade rapidly. In addition, early preclinical data has shown that by controlling the levels of specific microRNAs, cancer cell growth may be reduced. To learn more about microRNAs, please visit www.rosettagenomics.com.

About Rosetta Genomics
Rosetta Genomics develops and commercializes a full range of microRNA-based molecular diagnostics. Founded in 2000, the company’s integrative research platform combining bioinformatics and state-of-the-art laboratory processes has led to the discovery of hundreds of biologically validated novel human microRNAs. Building on its strong patent position and proprietary platform technologies, Rosetta Genomics is working on the application of these technologies in the development and commercialization of a full range of microRNA-based diagnostic tools. The Company’s miRview product line is commercially available through its Philadelphia-based CAP-accredited, CLIA-certified lab. To learn more, please visit www.rosettagenomics.com.

Forward-Looking Statements
Various statements in this release concerning Rosetta’s future expectations, plans and prospects, including without limitation, statements relating to the potential of microRNAs in the diagnosis and treatment of disease, constitute forward-looking statements for the purposes of the safe harbor provisions under The Private Securities Litigation Reform Act of 1995. Actual results may differ materially from those indicated by these forward-looking statements as a result of various important factors, including risks related to: Rosetta’s approach to discover microRNA technology and to work on the application of this technology in the development of novel diagnostics and therapeutic tools, which may never lead to commercially accepted products or services; Rosetta’s ability to obtain, maintain and protect its intellectual property; Rosetta’s ability to enforce its patents against infringers and to defend its patent portfolio against challenges from third parties; Rosetta’s need and ability to obtain additional funding to support its business activities; Rosetta’s dependence on third parties for development, manufacture, marketing, sales, and distribution of products; Rosetta’s ability to successfully develop its products and services; Rosetta’s ability to obtain regulatory clearances or approvals that may be required for its products and services; the ability to obtain coverage and adequate payment from health insurers for the products and services comprising Rosetta’s technology; competition from others using technology similar to Rosetta’s and others developing products for similar uses; Rosetta’s dependence on collaborators; and Rosetta’s short operating history; as well as those risks more fully discussed in the “Risk Factors” section of Rosetta’s Annual Report on Form 20-F for the year ended December 31, 2010 as filed with the Securities and Exchange Commission. In addition, any forward-looking statements represent Rosetta’s views only as of the date of this release and should not be relied upon as representing its views as of any subsequent date. Rosetta does not assume any obligation to update any forward-looking statements unless required by law.