USA Today -- Allow litigation, but make it hard to win cases against drugmakers. When the Food and Drug Administration approves a new drug as safe and effective, that isn’t always the end of the story. Sometimes, after the drug has been widely marketed, adverse effects start to appear. The most notorious recent example is Vioxx, the painkiller that went from new blockbuster medicine in 1999 to off the market in 2004, after studies showed a significantly higher risk of heart attack and stroke in certain patients. Read full story below.