EurekAlert -- Chemotherapy drugs often never reach the tumors they’re intended to treat, and radiation therapy is not always effective, because the blood vessels feeding the tumors are abnormal—"leaky and twisty” in the words of the late Judah Folkman, MD, founder of the Vascular Biology program at Children’s Hospital Boston. Now, Vascular Biology researchers have discovered an explanation for these abnormalities that could, down the road, improve chemotherapy drug delivery. Their findings were published in the August 12 issue of the Proceedings of the National Academy of Sciences.
