On the heels of Quebec's worst three-month jobs losses in a generation, Johnson & Johnson says it is closing its research centre in the province. New Jersey-based J&J, the world's biggest health care products company, told employees at its Montreal research and development centre Tuesday morning that the facility would shut down in March. Some 126 people work at the centre, including 36 J&J employees and 90 from a private placement agency hired on a contract basis, said the company's Quebec spokesperson, Laurent Pepin. The people are technicians, engineers and support staff working on feminine hygiene products made at the adjacent manufacturing plant.