NEW YORK--(BUSINESS WIRE)--ImClone Systems Incorporated (NASDAQ: IMCL), a leader in the development and commercialization of novel cancer therapeutics, today announced its financial results for the quarter and nine months ended September 30, 2007. Global net sales of ERBITUX® for the third quarter of 2007 were $351.4 million, compared to $284.8 million in the third quarter of 2006, an increase of 23%. U.S. in-market net sales of ERBITUX for the third quarter of 2007 were $184.5 million, of which approximately $9.0 million was attributable to a distribution model change that resulted in wholesaler inventory buildup during the quarter, compared to $174.6 million for the third quarter of 2006, an increase of 6%. International, or non-U.S., net sales of ERBITUX were $166.9 million, compared to $110.1 million for the third quarter of 2006, an increase of 52%. As compared to the second quarter of 2007, ERBITUX U.S. in-market sales and international sales increased by $22.4 million, or 14%, and $9.7 million, or 6%, respectively. The quarter-over-quarter increases in sales were due to accelerating demand for ERBITUX, along with the change in distribution model by Bristol-Myers Squibb (BMS) that also impacted U.S. in-market sales.