REGENSBURG, GERMANY--(Marketwire - December 16, 2008) - Today GENEART (FSE: G6A, Entry Standard Segment) and MorphoSys (FSE: MOR; Prime Standard Segment, TecDAX) announce their successful cooperation in the HuCAL PLATINUM® project. The application of GENEART's proprietary sequence design software GeneOptimizer® and production of significant parts of the antibody library allowed GENEART to make a large contribution to this project. Initial tests show that the HuCAL PLATINUM® translates into an up to 25 fold higher diversity compared to the previous version HuCAL GOLD®, and thereby provides more divers fully human antibodies as well as facilitating the selection of antibodies with a higher average affinity. Due to comprehensive sequence optimization, production rates of selected antibodies are significantly higher as well. Therefore, this next-generation antibody library does not only allow the identification of antibodies with improved characteristics but also the significant shortening of timelines for the development of promising drug candidates to pre-clinical studies.
