Ancient Egyptians were vexed by it, using sulfur to dry it out. Shakespeare wrote of its “bubukles, and whelks, and knobs, and flames o’ fire.” Today, acne plagues us still. Doctors can cure some cancers and transplant vital organs like hearts, but they still have trouble getting rid of the pimples and splotches that plague 85% of us at some time in our lives — usually, when we’re teenagers and particularly sensitive about they way we look.