Change In The Number Of Votes Relating To BioTie Therapies Corp.'s Shares

Biotie Therapies Corp. (Nasdaq Helsinki BTH1V; NASDAQ: BITI) (“Biotie” or the “Company”) announces that the Swiss subsidiary of the Company, Biotie Therapies AG (previously Synosia Therapeutics Holding AG and Biotie Therapies Holding AG) has conveyed Biotie shares against consideration pursuant to the option programs as follows:

October 2015 to date Total (5/2011-
10/2015 to date)
Options
outstanding
7,739 9,802,616 2,027,628

The conveyance of Biotie shares relates to the option plan of Synosia Therapeutics Holding AG (currently Biotie Therapies Holding AG, “Synosia”) acquired by Biotie in February 2011. According to such Synosia share option plan, options have been granted to employees, former directors and consultants. In connection with the completion of the acquisition of Synosia, the option plan was amended so that instead of shares in Synosia an aggregate maximum of 14,912,155 shares in Biotie may be subscribed based on the plan. Biotie issued these 14,912,155 shares to its current subsidiary Synosia in connection with the acquisition to be further conveyed to the option holders when they potentially exercise their option rights in accordance with the terms and conditions of the option program.

The conveyed shares previously held as Treasury shares have not carried any voting rights. The conveyance does not affect the number of registered shares.

After the conveyances the changes are as follows:

Increase in number of outstanding shares Total amount of
voting rights
Number of the
Company’s share held
by the Biotie Group
Total number
of registered
shares
7,739 978,253,983 108,686,288 1,086,940,271

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