ST. LOUIS, March 4 /PRNewswire-FirstCall/ -- Sigma, a division of Sigma- Aldrich Corporation , has launched a line of kits for glycoprotein analysis. This growing group of innovative kits provides an accurate, fast, and economic option for chemical and enzymatic deglycosylation and fluorescent glycan labeling. Featured products include GlycoProfile I In-Gel Enzymatic Deglycosylation Kit (Product Code PP0200), GlycoProfile II In-Solution Enzymatic Deglycosylation Kit (Product Code PP0201), GlycoProfile III Fluorescent Labeling Kit (Product Code PP0300), and GlycoProfile IV Chemical Deglycosylation Kit (Product Code PP0510). Each kit contains Proteomics Grade enzymes and standards and has been optimized to provide maximum yield in the shortest amount of time.
GlycoProfile(TM) I In-Gel Enzymatic Deglycosylation Kit (Product Code PP0200) N-Deglysosylates and tryptically digests glycoprotein samples in 1-D and 2-D poly acrylamide gel slices for subsequent MS or HPLC analysis. GlycoProfile(TM) II In-Solution Enzymatic Deglycosylation Kit (Product Code PP0201) Removes N-linked glycans from glycoproteins and is compatible with subsequent MALDI-TOF mass spectrophotometric analysis without interference from any of the reaction components. GlycoProfile(TM) III Fluorescent Labeling Kit (Product Code PP0300) Fluorescent detection of glycoproteins directly in PAGE gels without blotting or use of antibodies. GlycoProfile(TM) IV Chemical Deglycosylation Kit (Product Code PP0510) Chemically deglycosylates N- and O-linked glycoproteins with negligible protein degradation using trifluoromethansulfoxide.
"The launch of the GlycoProfile group of products is an exciting event that will significantly increase the pace at which glycoprotein research is performed in the lab, saving hours of preparation time and assuring accurate, consistent results. This line of kits is a new but quickly growing group of products that will continue to bring scientists from analysis to real answers each and every day!" said Michael Hadjisavis, Manager of Strategic Business, Protein Expression and Proteomics, at Sigma-Aldrich.
Sigma-Aldrich is a leading Life Science and High Technology company. Our biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and chemical manufacturing. We have customers in life science companies, university and government institutions, hospitals and in industry. Over one million scientists and technologists use our products. Sigma-Aldrich operates in 34 countries and has 5,900 employees providing excellent service worldwide. We are committed to the success of our Customers, Employees and Shareholders through leadership in Life Science, High Technology and Service.
This release contains forward-looking statements relating to future performance, goals, strategic actions and initiatives and similar intentions and beliefs and other statements regarding the Company's expectations, goals, beliefs, intentions and the like, which involve assumptions regarding Company operations and conditions in the markets the Company serves. The Company does not undertake any obligation to update these forward-looking statements.
To request information about GlycoProfile Kits or other Glycoprotein Analysis products, please visit sigma-aldrich.com. Glycoprotein Analysis Manual code: GDR.
Sigma-Aldrich CorporationCONTACT: Michael Hadjisavis, +1-314-286-7431, or Kim Harper,+1-314-286-8374, both of Sigma-Aldrich Corporation
Web site: http://www.sigma-aldrich.com/