CASTLE ROCK, CO--(Marketwire - December 17, 2008) - AspenBio Pharma, Inc. (NASDAQ: APPY), an emerging bio-pharmaceutical company dedicated to the development of novel drugs and diagnostics for humans and animals, announced the United States Patent and Trademark Office has issued a Notice of Allowance for AspenBio’s United States patent application directed to methods relating to its appendicitis diagnostic technology.