LOS ANGELES--(BUSINESS WIRE)--ZIOPHARM Oncology, Inc. (NASDAQ: ZIOP) announced today the presentation of preclinical data for an orally active form of ZIO-201 (isophosphoramide mustard - IPM) at the American Association of Cancer Research meeting being held in Los Angeles. Data presented demonstrated oral availability of ZIO-201 and activity in a variety of cancer models, including those with ifosfamide (IFOS) and cyclophosphamide resistant tumors. An oral form of IPM, the primary therapeutic component of IFOS, without the toxic metabolites of IFOS, could extend the therapeutic utility of ZIO-201 well beyond that of IFOS.
