High doses of vitamins do little to prevent a second stroke in patients who have already had one, according to a study published on Tuesday. The vitamins used in the study -- B6, B12 and Folic acid -- are believed to help lower blood levels of homocysteine, an amino acid thought to contribute to heart disease. To test whether vitamins would have an impact on recurring strokes researchers at Wake Forest University Baptist Medical Center looked at 3,680 people who had already suffered a non-disabling stroke and were being treated at 56 medical centers in the United States, Canada and Scotland.