British regulators issued a safety alert on Thursday after discovering packs of the over-the-counter painkiller Nurofen Plus containing the anti-psychotic drug Seroquel XL. The Medicines and Healthcare products Regulatory Agency (MHRA) issued the alert, potentially affecting thousands of packs, after receiving reports of rogue Seroquel XL tablets in three different batches of Nurofen Plus. The two medicines look very different but the MHRA said it had been informed that two patients took Seroquel XL instead of Nurofen Plus as a result of the unexplained packaging mix-up.