Targacept, Inc. Initiates Phase 2 Study of TC-5619 in Attention Deficit/Hyperactivity Disorder in Adults

WINSTON-SALEM, N.C.--(BUSINESS WIRE)--Targacept, Inc. (NASDAQ: TRGT), a clinical-stage biopharmaceutical company developing novel NNR Therapeutics (TM), today announced that it has initiated a Phase 2 clinical proof of concept trial of TC-5619 in adults with attention deficit/hyperactivity disorder (ADHD). TC-5619 is a novel small molecule that is highly selective for the alpha7 neuronal nicotinic receptor, which Targacept refers to as NNR, and was discovered by Targacept scientists using Targacept’s proprietary drug discovery platform known as Pentad (TM). Targacept expects this Phase 2 trial of TC-5619 to complete in the first half of 2011.

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