SYGNIS Signs Distribution Agreement With LABGENE Scientific For Switzerland

• ?LABGENE Scientific is a leading life science distributor focused on high quality products, reagents and consumables for use in molecular biology

• ?Agreement covers the entire SYGNIS portfolio of powerful tools for next generation sequencing (NGS) and single cell analysis (SCA) applications

Madrid, Spain and Heidelberg, Germany, September 17th, 2015 – SYGNIS AG (Frankfurt: LIO1; ISIN: DE000A1RFM03; Prime Standard) today announced that it has signed a distribution agreement with LABGENE Scientific for the commercialization of SYGNIS’ proprietary product portfolio in Switzerland.

Under the terms of the agreement, SYGNIS has granted LABGENE Scientific the rights to promote, market and sell all existing as well as future product lines to scientists working in genomics, proteomics and diagnostics in Switzerland. These product lines cover the Company’s revolutionary TruePrime™ products for primer-free whole genome amplification (WGA) as well as SunScript™ thermostable reverse transcriptase kits for the translation of RNA into DNA including the newly launched SunScript™ One Step Reverse Transcriptase (RT)-PCR Kit for parallel transcription and amplification of genomic information.

LABGENE Scientific is a specialist provider offering a broad portfolio of advanced and high quality products, reagents and consumables for molecular biology laboratories and facilities as well as platforms as integrated solutions for the life science research, diagnostic laboratories and the pharmaceutical industry.

“We are very pleased about this distribution agreement for our proprietary product portfolio with LABGENE Scientific, a well established distributor in Switzerland. In addition to its very dynamic academic life science environment, Switzerland is the home to many biotechnology and pharmaceutical companies, including the biggest of the world, and an important market for our products in Europe. Today, more than 40 life science companies have their international headquarters in Switzerland,” Pilar de la Huerta, CEO and CFO of SYGNIS commented. “With its wide customer network, LABGENE Scientific is best positioned to leverage the benefits of our existing as well as future products to customers in academic and pharmaceutical molecular biology and diagnostics laboratories in Switzerland.”

Beside the worldwide commercialization via a fast growing list of leading international distribution partners, the product portfolio can also be directly ordered via SYGNIS’ own online shop under http://www.sygnis.com/shop.

About TruePrime™

TruePrimeTM is the brand name of a revolutionary novel MDA technology and one of the key products in SYGNIS’ portfolio. TruePrimeTM is based on the combination of SYGNIS proprietary DNA primase “TthPrimPol” and the extremely processive and high-fidelity Phi29 polymerase to amplify uniformly total genomic DNA for a multitude of applications including next generation sequencing and single cell analysis. The extraordinary strand displacement capacity of the Phi29 polymerase allows TthPrimPol to generate new primers on the displaced strands that are extended by Phi29 DNA pol, resulting in exponential isothermal DNA amplification without the need of any synthetic random primers.

About SunScript™ RT

SunScriptTM RT is a reverse transcriptase that has been engineered for high thermostability, based on the well characterized human immunodeficiency virus RT (HIV-1 RT). The enzyme is active up to temperatures of 85°C. SunScriptTM Reverse Transcriptase will be available in two versions: SunScriptTM RT RNaseH+ is optimized for the synthesis of complementary DNA (cDNA) as well as for use in reverse transcriptase (RT) PCR and quantitative PCR reactions for use e.g. in clinical diagnostics whereas SunScriptTM RT RNaseH- permits high yields of full length cDNA synthesis on long RNA molecules for the construction of cDNA libraries needed for example in next generation sequencing (NGS) applications, in gene expression profiling and molecular diagnostics.

SYGNIS AG

Pilar de la Huerta
CEO/CFO
Phone: +34 91 192 36 50
Email: pdelahuerta@sygnis.com

MC Services AG
Raimund Gabriel
Managing Partner
Phone: +49 89 210228 30
Email: raimund.gabriel@mc-services.eu

About SYGNIS AG: www.sygnis.com

SYGNIS, headquartered in Germany and Spain, specializes on the development and commercialization of innovative products for DNA amplification and sequencing. Based on its proprietary technologies, SYGNIS has developed a commercial product portfolio addressing key challenges in the fast growing fields of molecular biology and next generation sequencing applications. Key products include the TruePrime™ product line and SensiPhi®, licensed to an industry leading partner, for whole genome DNA amplification and sequencing as well as the SunScript™ Reverse Transcriptase product family to convert genetic information from RNA molecules back to DNA. SYGNIS AG is listed at the German Stock Exchange in the Prime Standard segment (Ticker: LIO1; ISIN: DE000A1RFM03).

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