CAMBRIDGE, Mass.--(BUSINESS WIRE)--Seaside Therapeutics, Inc. announced today data from the largest randomized, placebo-controlled study conducted to date in individuals with fragile X syndrome. In a Phase 2 study of STX209, clinically meaningful improvements on global and specific neurobehavioral outcomes were observed in the general study population. The improvements were statistically significant in pediatric patients with more severe impairments in sociability -- a core symptom of fragile X syndrome. STX209 is a selective gamma-amino butyric acid type B (GABA-B) receptor agonist. The results were presented in a podium presentation at the National Fragile X Foundation’s 12th International Fragile X Conference in Michigan on Saturday, July 24, 2010 by investigators Elizabeth Berry-Kravis, MD, PhD, Professor of Pediatrics, Neurological Sciences and Biochemistry at Rush University Medical Center in Chicago, Illinois and Randi Hagerman, MD, Medical Director, M.I.N.D. Institute, Professor, Endowed Chair in Fragile X Research, School of Medicine, University of California, Davis, in Sacramento, California. Seaside continues to conduct additional analyses of other outcome measures and biomarker data sets and intends to submit full results for publication.
