Sangamo BioSciences, Inc. To Participate In HIV Workshop And To Present At Biotechnology Industry Organization (BIO) CEO & Investor Conference 2007

RICHMOND, Calif., Feb. 7 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. announced today that Edward Lanphier, Sangamo’s president and chief executive officer, will provide an overview of the company’s business strategy and an update on the progress of Sangamo’s therapeutic development programs at the BIO CEO & Investor Conference 2007 in New York on Wednesday, February 14, 2007 at 1:30 p.m. (ET).

The presentation will be webcast live and may be accessed via a link on the Sangamo BioSciences website in the Investor Relations section under “Company Overview” http://phx.corporate-ir.net/phoenix.zhtml?c=120938&p=irol-IRHome . The presentation will be archived on the Sangamo website for two weeks after the event.

Mr Lanphier is also an invited speaker at the Therapeutic Workshop, “Novel HIV Therapies - Still Room for Improvement”, that will be held on Monday, February 12 at 3:30 pm (ET). This event will also be webcast and will be available on the BIO CEO and Investor Conference website http://ceo.bio.org/opencms/ceo/2007/index.jsp

About Sangamo

Sangamo BioSciences, Inc. is focused on the research and development of novel DNA-binding proteins for therapeutic gene regulation and modification. The most advanced ZFP Therapeutic(TM) development program is currently in a Phase 2 clinical trial for evaluation of safety in patients with diabetic neuropathy. Phase 1 clinical trials are ongoing to evaluate a ZFP Therapeutic for peripheral artery disease. Other therapeutic development programs are focused on ischemic heart disease, neuropathic pain, cancer and infectious and monogenic diseases. Sangamo’s core competencies enable the engineering of a class of DNA-binding proteins known as zinc finger DNA-binding proteins (ZFPs). By engineering ZFPs that recognize a specific DNA sequence Sangamo has created ZFP transcription factors (ZFP TFTM) that can control gene expression and, consequently, cell function. Sangamo is also developing sequence-specific ZFP Nucleases (ZFNTM) for therapeutic gene modification as a treatment for a variety of monogenic diseases, such as X-linked SCID and hemophilia, and for infectious diseases, such as HIV. Sangamo has established several Enabling Technology Agreements with companies to apply its ZFP Technology to enhance the production of protein pharmaceuticals. For more information about Sangamo, visit the company’s web site at http://www.sangamo.com/ .

This press release may contain forward-looking statements based on Sangamo’s current expectations. These forward-looking statements include, without limitation, references to the research and development of novel ZFP TFs and ZFNs, applications of Sangamo’s ZFP TF technology platform and clinical trials of ZFP Therapeutics. Actual results may differ materially from these forward-looking statements due to a number of factors, including technological challenges, uncertainties relating to the initiation and completion of stages of the ZFP Therapeutic clinical trials, Sangamo’s ability to develop commercially viable products and technological developments by our competitors. See the company’s SEC filings, and in particular, the risk factors described in the company’s Annual Report on Form 10-K and its most recent 10-Q. Sangamo BioSciences, Inc. assumes no obligation to update the forward-looking information contained in this press release. Contact

Sangamo BioSciences, Inc.

CONTACT: Elizabeth Wolffe, Ph.D., of Sangamo BioSciences, Inc.,+1-510-970-6000, ext. 271, or ewolffe@sangamo.com; or media, JustinJackson, of Burns McClellan, Inc., +1-212-213-0006, orjjackson@burnsmc.com, for Sangamo BioSciences, Inc.

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