SAN DIEGO--(BUSINESS WIRE)--Nereus Pharmaceuticals, Inc., a pioneer in drug discovery from marine microbial sources, today announced that enrollment has begun in a Phase 1b study evaluating the proteasome inhibitor NPI-0052 in combination with vorinostat (Zolinza®, Merck & Co.) in patients with selected solid tumor malignancies. The open-label study will enroll approximately 40 patients with advanced non-small cell lung cancer, pancreatic cancer or melanoma for whom standard approved therapy is not available. The study follows on positive outcomes from preclinical studies of the combined agents and clinical trials with NPI-0052.
