NeoPharm Announces Completion Of PRECISE Trial Enrollment As Per Special Protocol Assessment Agreement

WAUKEGAN, Ill.--(BUSINESS WIRE)--Dec. 9, 2005--NeoPharm, Inc. (Nasdaq:NEOL) today announced that it has received notification that the Company's cintredekin besudotox (IL13-PE38QQR) Pivotal Phase III PRECISE trial for the treatment of Glioblastoma Multiforme (GBM), the most aggressive form of brain cancer, has achieved the 270 intent-to-treat patient enrollment milestone, as established by the PRECISE Trial protocol. As previously reported, the PRECISE Trial protocol allows for enrollment of up to 300 patients in order to obtain 270 patients with confirmed GBM at first recurrence at study entry surgical resection, for the intent-to-treat patient population. Only 288 patients were required to be enrolled to meet the 270 intent-to-treat patient population.
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