(BUSINESS WIRE)--MedImmune, the global biologics unit of AstraZeneca PLC (NYSE: AZN) and Micromet, Inc. (NASDAQ: MITI) today announced the initiation of a Phase 1 trial of MEDI-565 (MT111) in patients with advanced gastrointestinal cancers. MEDI-565 (MT111) is a BiTE® antibody designed to direct a patient’s T cells, the body’s most potent killer cells, against cancer cells that express carcinoembryonic antigen (CEA). CEA is a protein found on the surface of a number of gastrointestinal cancers, including colorectal, pancreatic, esophageal and gastric.