IsoTis OrthoBiologics To Release Full Year 2005 Results On February 27

LAUSANNE, Switzerland and IRVINE, California, February 16 /PRNewswire-FirstCall/ -- IsoTis OrthoBiologics will release its full year 2005 results on February 27 before the financial markets open. To discuss these results, the Company will hold a meeting with the financial community at SWX Convention Point in Zurich and simultaneously conduct a conference call at 3.00 p.m. CET/9.00 a.m. ET/6.00 a.m. PT.

The call will be Webcast live on the IsoTis website at www.isotis.com (- investors - IR investor center). To participate in the conference call, dial: +41-91-610-5609 (Europe); +44-20-7107-0613 (UK); +1-866-865-5-44 (toll free dial in US/Canada); no password required. Digital playback is available for 24 hours after the conference starting at 6.00 p.m. until February 28, 6.00 p.m. CET, dial: +41-91-612-4330 (Europe); +44-20-7108-6233 (UK); +1-866-416-2558 (US/Canada); Conference ID: 238#. The Webcast will remain available on IsoTis’ website at least through April 30, 2006.

About the company:

IsoTis OrthoBiologics has a product portfolio with several innovative and proprietary natural and synthetic bone graft substitutes on the market and others in development, an established North American independent distribution network, and an expanding international presence. The company’s main commercial operations are based out of Irvine, CA; its international sales headquarters is based in Lausanne, Switzerland.

IsoTis OrthoBiologics

CONTACT: For information contact: Hans Herklots, Director IR, Tel:+41(0)21-620-6011, E-mail: hans.herklots@isotis.com, Rob Morocco, CFO,+1-949-855-7158, robert.morocco@isotis.com

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