World ADC London is Europe’s longest standing and definitive antibody-drug conjugate (ADC) event dedicated to maximizing the therapeutic window of ADCs. Dr. Robinson will give a platform talk on Wednesday, March 15 discussing how Immunome’s Discovery Engine can highlight novel target classes which have relevance for multiple therapeutic modalities, including ADCs. Full presentation details are included below.

“Human memory B cells are able to record the targets that are classified as important attack points for antibodies across the course of tumor development. With our proprietary Discovery Engine, we can harness this information through an unbiased interrogation of the patient memory B cell response – at an industrial scale – to identify novel targets and antibodies that bind them,” Dr. Robinson commented. “Our research has revealed novel target classes, such as proteins abnormally expressed on the surface of cancer cells, which we believe are uniquely tumor selective and potentially suitable for development as ADCs. With the help of our newly established Antibody-Drug Conjugate and T Cell Redirection Advisory Board, I look forward to further exploring how we can apply this approach to advance new ADC therapeutics and improve cancer treatment.”

Presentation Details:

Title: Harnessing the Power of the Human Memory B Cell

Presenter: Matthew Robinson, Ph.D., Chief Technology Officer

Date: March 15, 2023, 12:00 p.m. GMT / 7:00 a.m. ET

A copy of the presentation will be available on the Events & Presentations section of Immunome’s website following the conference.

About Immunome

Immunome is a biopharmaceutical company that utilizes its proprietary human memory B cell platform to discover and develop antibody therapeutics to improve patient care. The company’s focus is on discovering and developing therapeutics in oncology internally and in collaboration with our partners. For more information, please visit www.immunome.com or follow us on Twitter and LinkedIn.

About Immunome’s Discovery Engine

Immunome’s proprietary Discovery Engine identifies novel therapeutic antibodies and their targets through an unbiased interrogation of human memory B cells, highly educated components of the immune system, isolated from patients. Memory B cells are key elements in the human immune system response to disease as they produce specific, high-affinity antibodies that bind to cancer antigens or pathogens. Immunome’s Discovery Engine incorporates high-throughput screening to enable efficient, unbiased, broad, and deep functional evaluation of patient memory B cell repertoires to identify antibodies directed at novel targets. The functional data we generate differentiates our approach from those that use deep sequencing of B cells to identify dominant clones that are common within and across patients and assumes genomic dominance is a hallmark of therapeutic utility.

For more information, please visit www.immunome.com.

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