The poster presentation will describe the rationale and design of the combination study with KEYTRUDA and BGB324, a first-in-class and highly selective small molecule Axl kinase inhibitor, which is being developed to target tumour immune evasion and resistance.
Bergen, Norway, 14 Nov 2017 – BerGenBio AS (OSE:BGBIO), a clinical-stage biopharmaceutical company developing novel, selective Axl kinase inhibitors for multiple cancer indications, is pleased to announce that the Company will present its recently initiated Phase II clinical trial investigating BGB324 in combination with the Merck & Co., Inc., Kenilworth, N.J., USA (known as MSD outside the United States and Canada) anti-PD-1 therapy, KEYTRUDA® (pembrolizumab), in patients with triple negative breast cancer (TNBC) at the 2017 San Antonio Breast Cancer Symposium in San Antonio, USA (5-9 Dec 2017).
The poster presentation will describe the rationale and design of the combination study with KEYTRUDA and BGB324, a first-in-class and highly selective small molecule Axl kinase inhibitor, which is being developed to target tumour immune evasion and resistance.
The poster will be presented by Murray Yule (MD, PhD) Clinical Development Officer at BerGenBio, and is entitled: A Phase II multi-center study of BGB324 in combination with pembrolizumab in patients with previously treated, locally advanced and unresectable or metastatic triple negative breast cancer (TNBC) or triple negative inflammatory breast cancer (TN-IBC)
- Abstract ID#: 851840 – Henry B. Gonzalez Convention Center, San Antonio, USA, 9-12 Dec 2017
- Session: Ongoing Trials – Immunotherapy, OT1 – Wednesday, 6 Dec 2017, 5pm-7pm
- ClinicalTrials.gov identifier: NCT03184558
